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Willow & OakAesthetic Collective

Botox vs. Xeomin: How to Choose

Marjorie Lantum, M.D.
Two unlabelled glass vials on linen

We carry both Botox and Xeomin, and both are $12 per unit. So the question people ask is a genuinely open one: if the price is the same, why pick one over the other?

They are the same category, not the same product

Both are injectable neuromodulators. Both are prescription medical products, administered by a provider. Broadly, they work the same way — by temporarily reducing the activity of the specific muscle they are placed in.

Where they differ is formulation. Botox carries accessory proteins alongside the active ingredient. Xeomin is manufactured without them — it is sometimes described as a "naked" formulation for that reason.

Does that difference matter to you?

Sometimes, and it is worth being careful here, because this is an area where marketing tends to outrun the evidence.

The theoretical argument for Xeomin is that fewer accompanying proteins means less for the immune system to respond to. In practice, the people for whom this is most likely to come up are those who have had a lot of neuromodulator treatment over a long period and feel it has become less effective for them.

Whether that applies to you is a clinical judgement, made by a provider who can ask about your history. It is not something to settle from a blog post — ours included.

Dosing is not interchangeable

The two products are not measured against each other one-for-one. Your provider will work out the appropriate number of units for whichever product is being used, which means the unit count — and so the total — can differ even at the same per-unit price.

Ask for your total before treatment starts, whichever product you are having.

How the decision actually gets made

At your consultation, expect your provider to ask about:

  • Whether you have had neuromodulator treatment before, and how it went
  • How long previous results lasted, if you have had it before
  • Which area you want treated and what you are hoping for
  • Your medical history, medications, and anything relevant going on right now

Then they will recommend one. If you have a preference, say so — it is a reasonable thing to discuss. But the recommendation should come from the clinical picture, not from whichever product is being promoted that month.

What we will not tell you

We will not tell you that one is better. They are different products with different formulations, both widely used, and the right choice depends on the person in the chair. Any clinic that gives you a universal answer to this question is telling you about their inventory rather than your face.

What actually varies between clinics

Since the products are widely available, the meaningful differences between providers are not the vials. They are:

  • Who injects. Training and experience vary enormously, and this is the single largest variable in your result.
  • How long the assessment is. A provider who watches your face move before deciding where anything goes is doing something a rushed appointment cannot.
  • Whether you are told your total in advance.
  • What happens afterwards. Who you call, how quickly you are seen, whether follow-up is offered.

Those are the questions worth asking anywhere, including here.

Common questions

Can I switch between them?

This is a conversation to have with your provider, who will consider your history and what you are hoping for. Do not assume a straight swap at the same dose.

Will one last longer than the other for me?

Individual. Your provider will have a better answer after seeing how you respond, which is one reason the first appointment is as much information-gathering as treatment.

Is one more natural-looking?

The product is not what produces a natural result — placement and dose are. That is about the person holding the syringe, not the label on the vial.

I have been told a product "stopped working" for me. What now?

Bring that history to your consultation in as much detail as you can remember. It is directly relevant to the recommendation, and it is one of the few situations where the formulation difference genuinely enters the discussion.

Do you use the same price for both?

Yes, $12 per unit for either. The unit count can differ, so ask for your total.

Booking

Consultations are how this gets decided. If you are in Hendersonville or the surrounding Sumner County area, book one and we will talk it through properly.

Every plan here is set at consultation. Prices are starting prices and are subject to change; package pricing is given at consultation.

Information on this site is for general purposes only and is not medical advice. Individual results vary. All medical services are provided following consultation with a licensed provider.